Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp158 | Cancer and bone: basic, translational and clinical | ECTS2013

Role of receptor activity modifying proteins in skeletal regulation

Pacharne Suruchi , Richards Gareth , Wang Ning , Skerry Timothy , Caron Kathleen

Receptor activity modifying proteins (RAMPs 1, 2 and 3) are a class of important accessory proteins that interact and regulate several G-protein coupled receptor (GPCR) activity by finely modulating ligand interaction and in some cases trafficking receptors to cell surface.Predominant roles of RAMPs include ligand selectivity in receptors for Calcitonin (CT) family of peptides that comprise calcitonin, calcitonin gene related peptide, amylin and Adrenome...